“The work began only a few months before I started but continued throughout the entire duration of my time at Tufts University so I was a major contributor for the project.” “As third author on this paper, I participated in surgery, animal care, and all post-processing of samples such as RNA extraction and analysis, immunohistochemistry, imaging, and more,” she said. The title is: “Acute multidrug delivery via a wearable bioreactor facilitates long-term limb regeneration and functional recovery in adult Xenopus lavis” – a species commonly known as African clawed frogs: She explained her own role in the research leading to the article, for which she receives a credit. Inspiring the widespread media attention was a paper appearing recently in the journal Science Advances, with lead authors including Michael Levin who directs the Allen Discovery Center at Tufts, where Miller worked from 2018 to late 2020 as a key team member. It is a long way from re-growing an amputated human leg, but it is exciting way to get the ball rolling!” “But also a great first step to beginning exploration of this kind of treatment in mammalian models. “This is a very amazing first step toward exploring application of short-term drug cocktails rather than long-term treatments for re-growing limbs in amphibians,” Miller said in response to a Saint Michael’s inquiry about the research. The Guardian report cut most clearly to the chase: “A frog has regrown a lost leg after being treated with a cocktail of drugs in a significant advance for regenerative medicine,” read the major international paper’s report about a discovery by a group of Tufts University researchers that included Miller. Kelsie Miller, a 2016 Saint Michael’s biology graduate, had a key role in some recent science news that was exciting enough to rate reports in The New York Times, Wall Street Journal, England’s Guardian, Smithsonian Magazine and even a mention during comedian Stephen Colbert’s “Meanwhile” segment of his popular late-night show. The large photo behind the headline shows Kelsie doing fish research on a boat on Lake Champlain during her St. Kelsie Miller ’16, center, with Hannah Vigran (second listed author on the recently highly publicized paper, and Nirosha Murugan (first author) from Kelsie’s time at Tufts.
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